Minireview: Insights into anti-interferon-γ autoantibodies
نویسندگان
چکیده
منابع مشابه
Immune Alterations in Patients with Anti-Interferon-γ Autoantibodies
Autoantibodies against interferon-gamma (IFN-γ) can cause immunodeficiency and are associated with various opportunistic infections. In the present study, we investigated other cellular immune parameters for a better understanding of the immunodeficiency condition in the patients. The numbers of WBC, monocytes and NK cells were increased in patients with anti-IFN-γ autoantibodies (AAbs). Upon T...
متن کاملDisseminated Talaromyces marneffei and Mycobacterium abscessus in a Patient With Anti-Interferon-γ Autoantibodies
Anti-interferon (IFN)-γ autoantibodies are increasingly recognized as a cause of adult-onset immunodeficiency and increased risk for infections with intracellular pathogens. We report on disseminated Talaromyces (Penicillium) marneffei and Mycobacterium abscessus infection in a 72-year-old, human immunodeficiency virus noninfected, Thai man with anti-IFN-γ autoantibody. The patient was successf...
متن کاملInterferon-γ Autoantibodies as Predisposing Factor for Nontuberculous Mycobacterial Infection
Author affiliations: Hospices Civils de Lyon, International Center for Research in Infectiology, Université Claude Bernard Lyon 1, INSERM U1111, Lyon, France (F. Valour, T. Perpoint, A. Sénéchal, T. Ferry, C. Chidiac, F. Ader); Necker-Enfants Malades Hospital, INSERM, Paris Descartes University, Paris, France (J. Bustamante); St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockef...
متن کاملAnti-Interferon Autoantibodies in Autoimmune Polyendocrinopathy Syndrome Type 1
BACKGROUND The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM 240300), recessive AIRE mutations lead to autoimmunity targetting endocrine and other epithelial tissues, although chronic candidiasis usually appears first. Autoimmunity and chronic candidiasis can associate with thymomas as well. Patients wit...
متن کاملP 204 Title: Anti-α, anti-β, and anti-γ-crystallin autoantibodies from patients with cataract
Purpose Anti-crystallin autoantibodies have been often demonstrated in patients with cataract but only few studies point out on autoantibodies directed against the different crystallin classes. Our aim was to determmr the prevalence of antI-a-, anti-p, or antI-7 crystalho autoantibodIes m sera from 54 patients with lugh level of anti-total lens extract antibodies in comparison to control group ...
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ژورنال
عنوان ژورنال: Experimental Biology and Medicine
سال: 2021
ISSN: 1535-3702,1535-3699
DOI: 10.1177/1535370220981579